AV俱乐部

Dr. Zeeshan Sheikh is a聽Clinical Scientist in Periodontics, Assistant Professor-Tenure-Track聽in the departments of聽Applied Oral Sciences (AOS) and聽Dental Clinical Sciences聽(DCS) at the Faculty of Dentistry-AV俱乐部.聽Dr. Sheikh is a Fellow of The Royal College of Dentists of Canada (RCDC) in the field of Periodontics. Dr. Sheikh was trained as a dental clinician and a biomaterial scientist with clinical and research degrees of Dip.Dh, BDS, MSc, PhD and M.Perio in the fields of biomaterials research, clinical dentistry and surgical periodontics and implantology. He has more than 6 years of clinical experience in private and hospital-based dentistry. After graduating as a dentist, he worked as a dental surgeon for 2 years before proceeding to obtain an MSc degree in dental and biomaterials from Queen Mary, University of London (QMUL) with distinction. He obtained a PhD from McGill University, Faculty of Dentistry (2010-2014). He completed 2 Post-Doctoral Fellowships at Faculty of Dentistry, University of Toronto, The Mt. Sinai Hospital (Lunenfeld-Tanenbaum Research Institute) in Toronto, Canada and The Department of Laboratory Medicine and Pathology, Faculty of Medicine, University of Toronto (2015-2019). He completed his residency in Periodontics & Implant Surgery from AV俱乐部 (2019-2022) and also obtained a Masters of Periodontics degree (M.Perio).

In addition to delivering several conference talks, presentations and CE courses both locally in Canada and internationally, Dr. Sheikh has several research publications, reviews, book chapters, case-reports and editorials in peer-reviewed and other journals. He has also co-edited three textbooks on Oral Biology and Dental Biomaterials. He is also the recipient of several research awards and prizes. Being trained extensively as a clinician scientist in institutions like the Baqai Medical University, Queen Mary University of London, McGill University, University of Toronto and AV俱乐部, his research expertise lies in developing novel biomaterial options for bone grafting and alveolar ridge augmentation applications. He has in the past and continues to collaborate extensively with industry and was recently the President of the CADR-NCOHR NSRG and was also the representative for AV俱乐部 on the NCOHR communications committee. He is currently the Chair for the NCOHR-Knowledge Exchange Working Group.

Dr. Zeeshan Sheikh鈥檚 career is an amalgamation of the skills acquired during the MSc, PhD, Post-Doctoral training and Periodontics Specialty Training to allow the carrying out of funded collaborative translational research. Dr. Sheikh aims to continue working as a clinician-scientist in the fields of Periodontics and Biomaterials and become a contributing member of the academic community in Canada.

Publications:

• Dicalcium phosphate cements: Brushite and monetite.聽Faleh Tamimi,聽Zeeshan Sheikh, Jake Barralet. Acta Biomaterialia 8 (2012) 474鈥�487

• The effect of autoclaving on the physical and biological properties of dicalcium phosphate dihydrate bioceramics: brushite vs. monetite.聽Faleh Tamimi, Damien Le Nihouannen, Hazem Eimar,聽Zeeshan Sheikh, Svetlana Komarova, Jake Barralet. Acta Biomaterialia.2012 Aug; 8(8)

• Reproducible quantification of osteoclastic activity: characterization of a biomimetic calcium phosphate assay.聽Salwa Maria, Christiane Prukner,聽Zeeshan Sheikh, Frank Mueller, Jake Barralet, Svetlana V Komarova. Journal of Biomedical Materials Research: Part B: Applied Biomaterials (2013)

• Matrix metalloproteinases and their pathological upregulation in multiple sclerosis: an overview.聽Javaid, M.A, Abdallah, M.N., Ahmed, A.S. and聽Sheikh, Z Acta Neurol Belg DOI 10.1007/s13760-013-0239-x

• Nociception and role of immune system in orofacial pain.聽Vivek Varma,聽Zeeshan Sheikh, Ahad Ahmed. Acta Neurol Belg. 2014: 1-8

• Dental Biomaterials and a novel composite of zirconia and poly ether ether ketone for dental implants.聽Murali Ramamoorthi, Vivek Verma,聽Zeeshan Sheikh.聽IDJSR. January. 2015, volume 2

• Oral antimicrobial peptides: Types and role in the oral cavity.聽Zohaib Khurshid, Mustafa Naseem,聽Zeeshan Sheikh, Shariq Najeeb, Sana Shahab, Sohail Zafar. Saudi Pharmaceutical Journal. March (2015)聽

• Characterization of biomimetic calcium phosphate labeled with fluorescent dextran for quantification of osteoclast activity,聽Salwa Maria, Christiane Prukner,聽Zeeshan Sheikh, Frank Mueller, Svetlana V Komarova, Jake Barralet. Acta Biomateralia.

• Bone regeneration using bone morphogenetic proteins and various biomaterial carriers.聽Materials 2015, 8(4), 1778-1816; doi:10.3390/ma8041778.聽Zeeshan Sheikh, Mohammad Ahmad Javaid, Nader Hamdan, Raheel Hashmi

• Chelate setting of alkali ion substituted calcium phosphates.聽Zeeshan Sheikh, Martha Geffers, Jake Barralet, Uwe Gbureck. Ceramics International. 2015

• In vitro degradation and in vivo resorption of dicalcium phosphate cement based grafts..聽Zeeshan Sheikh, Yu Ling Zhang, Liam Grover, Faleh Tamimi, Jake Barralet. ActaBiomaterialia. 2015 Doi:

• Biodegradable materials for bone repair and tissue engineering applications..聽Zeeshan Sheikh, Sharique Najeeb, Zohaib Khurshid, Vivek Varma, Haroon Rashid, Michael Glogauer. Materials 2015,聽8, 5744-5794; doi:10.3390/ma8095273

• Macrophages and their interactions with implantable biomaterials..聽Zeeshan Sheikh, Patricia Brooks, Oriyah Barzilay, Noah Fine, Michael Glogauer.. Materials 2015,聽8(9), 5671-5701; doi:10.3390/ma8095269

• Mechanisms of in vivo degradation and resorption of calcium phosphate based biomaterials..聽Zeeshan Sheikh, Mohamed-Nur Abdallah, Ahmed Abdalla Hanafi, Syed Misbahuddin, Harron Rashid, Michael Glogauer. Materials 2015, 8(11), 7913-7925; doi:10.3390/ma8115430.

• Surface modifications of dental implants by incorporation of roughness and hydroxyapatite coatings.聽Zeeshan Sheikh, Fahd Ahmed, Yuliya Mulyar, Sadaf Farookhi, Haroon Rashid, Vivek Varma, Murai Khalifa. JPDA, Vol. 24 No. 04 Oct-Dec 2015.

• Protein Adsorption Capability on Polyurethane and Modified-Polyurethane Membrane for Periodontal Guided Tissue Regeneration Applications.聽Zeeshan Sheikh, Abdul Samad Khan, Nima Roohpour, Michael Glogauer, Ihtesham Rehman.聽Materials Science and Engineering C. Vol 68, 1st聽November 2016

• Controlling Bone Graft Substitute Microstructure to Improve Bone Augmentation.聽Zeeshan Sheikh, Yu Ling Zhang, Justin Drager, M Nur Abdallah, Faleh Tamimi, Jake Barralet.聽Advanced Healthcare Materials. 19 May 2016. DOI: 10.1002/adhm.

• Bifunctionality of Hypoxia Mimics in Bioceramic Bone Repair.聽Justin Drager,聽Zeeshan Sheikh, Yu Ling Zhang, Edward Harvey, Jake Barralet.聽Acta Biomaterialia,聽(42) 15 Sept, 2016聽

• Collagen based barrier membranes for periodontal regeneration applications.聽Zeeshan Sheikh, Javairia Qureshi, M Al-Shahrani, Hiba Nasar, Yuichi Ikeda, Michael Glogauer, Bernhard Ganss.聽翱诲辞苍迟辞濒辞驳测.听September, 2016. DOI: 10.1007/s10266-016-0267-0

• Effect of processing conditions of dicalcium phosphate cements on graft resorption and bone formation.聽Zeeshan Sheikh, Yu Ling Zhang, Faleh Tamimi, Jake Barralet.聽Acta Biomaterialia.聽February, 15th, 2017.聽

• Natural graft tissues and synthetic biomaterials for periodontal repair, regeneration and alveolar bone reconstructive applications: A review.聽Zeeshan Sheikh, Nader Hamdan, Yuichi Ikeda, Marc Grynpas, Bernhard Ganss, Michael Glogauer, Biomaterials Research. 2017 21:9. DOI: 10.1186/s40824-017-0095-5

• Resveratrol derivative-rich melinjo seed extract induces healing in a murine model of established periodontitis.聽Yuichi Ikeda, Yongqiang Wang, Noah Fine,聽Zeeshan Sheikh, Oriyah Barzilay, Bernhard Ganss, Howard C Tenenbaum, Michael Glogauer.聽Journal of periodontology 89 (5), 586-595

• Comparative adsorption profiles of basal lamina proteome and gingival cells onto dental and titanium surfaces.聽M Nur Abdallah, Ghada Abuelghanam,聽Zeeshan Sheikh, Simon Tran, Faleh Tamimi..聽Acta biomaterialia 73, 547-558a聽2018

• Resolving Macrophages Counter Osteolysis by Anabolic Actions on Bone Cells.聽Ana Viniegra, Hailey Goldberg, Noah Fine,聽Zeeshan Sheikh, Marcelo Freire, Yongqiang Wang, Thomas E Van Dyke, Michael Glogauer and Corneliu Sima.聽Journal of dental research聽97 (10), 1160-1169)

• Improved Alveolar Ridge Augmentation Using Synthetic Monetite Based Onlay Grafts.聽Zeeshan Sheikh聽and Michael Glogauer.聽Oral Health Journal聽July 2018

• A novel anabolic conjugate (C3) in the matrix of dicalcium phosphate onlay block grafts for achieving vertical bone augmentation: an experimental study on rabbit calvaria.聽Zeeshan Sheikh, Gang Chen, Marion Thevenin, Robert Young, Marc Grynpas, Michael Glogauer.聽Journal of oral and maxillofacial implants. DOI: 10.11607/jomi.7236

• Differential response of human blood leukocytes to brushite, monetite and calcium polyphosphate biomaterials.聽Noah Fine*,聽Zeeshan Sheikh*, Faik Al Jaf, Morvarid Oveisi, Alon Borenstein, Youxin Hu, Robert Pilliar, Marc Grynpas, Michael Glogauer.*First authorship shared.聽Journal of Biomedical Materials Research: Part B - Applied Biomaterials.聽22 April 2019聽

• A Novel Anabolic Conjugate (C3) in the Matrix of Dicalcium Phosphate Onlay Block Grafts for Achieving Vertical Bone Augmentation: An Experimental Study on Rabbit Calvaria..聽Zeeshan Sheikh; Gang Chen; Th茅venin, Marion; Young, Robert N.; Grynpas, Marc D.; Glogauer, Michael.聽International Journal of Oral & Maxillofacial Implants . Jul/Aug2019, Vol. 34 Issue 4, pe51-e63. 13p.

• In Vivo Bone Effects of a Novel Bisphosphonate-EP4a Conjugate Drug (C3) for Reversing Postmenopausal Bone Loss in an Ovariectomized Rat Model.聽Zeeshan Sheikh, Gang Chen, Faik Al Jaf, Marion Thevenin, Kate Banks, Micheal Glogauer, Robert Young, Marc Grynpas.聽Journal of Bone and Mineral Research Plus. 16 September 2019聽

• Achieving enhanced bone regeneration using monetite granules with bone anabolic drug conjugates (C3 and C6) in rat mandibular defects.聽Zeeshan Sheikh,聽Mohamed鈥怤ur Abdallah, Faik Al鈥怞af, Gang Chen, Nader Hamdan, Robert N Young, Marc D. Grynpas, Michael Glogauer.聽Journal of Biomedical Materials Research Part B: Applied Biomaterials. 11 March 2020聽

• Improved bone regeneration using bone anabolic drug conjugates (C3 and C6) with deproteinized bovine bone mineral as a carrier in rat mandibular defects.聽Zeeshan Sheikh,聽Mohamed鈥怤ur Abdallah, Faik Al鈥怞af, Gang Chen, Nader Hamdan, Robert N Young, Marc D. Grynpas, Michael Glogauer.聽Journal of Periodontology. 25 February 2020聽

• Immune response to implanted bone replacement graft materials.聽Zeeshan Sheikh, Nader Hamdan, Haider Al-Waeli, Michael Glogauer. Oral Health Journal. 15th聽December, 2020